Absorption Study

Dr. Nikolai Daskaloff
Investigation into the Absorption Behaviour of Activated Clinoptilolite in the Digestive Tract by Isotopic Marking
Publication
November 2005, Study (Studie)
Summary:
Dr. Nikolai Daskaloff conducted an in vivo study of the absorption of modified and activated clinoptilolite (MAC) in the human digestive tract. For the experiment he used Toxaprevent and marked it using the radioactive isotope technetium-99m. This isotope would, without coupling to clinoptilolite, be completely absorbed into the intestinal tract, and the radiation would be detectable in organs other than the gastrointestinal tract.
The study showed that activated clinoptilolite (MAC) is not absorbed in the human digestive tract and thus, again, completely excreted. MAC spent the majority of time in the gastrointestinal tract. Thus, MAC can exert its effect and absorb heavy metals and toxins here. In the experiment, the time between ingestion and excretion was approximately 24 hours. There was no radiation measured in the thyroid, lungs or kidneys, which would have indicated the absorption of MAC.


The research results presented below are only the beginning of larger research projects and preparation of subsequent publications in scientific journals. The research project for the study of the absorption of activated clinoptilolite in the human digestive tract is a private research project that was carried out in collaboration with the Research Centre Rossendorf, Insitute of Bioinorganic and Radiopharmaceutical Chemistry. Activated clinoptilolite (MAC) from Froximun AG was used as the subject. The experimental model is characterised by the coupling of activated clinoptilolite to an isotopic substance and the measurement of radiation and distribution in the human body by self-experimentation. The first task of the experiment was the labelling of the clinoptilolite with a suitable isotope. The problem here was to make sure the isotope-MAC bond was suitable for the highly acidic and basic milieu of the gastrointestinal tract. Through collaboration with the Institute of Bio-inorganic and Radio-pharmaceutical Chemistry, Technetium-99m was finally determined as the most appropriate chemical for the trials.
Technetium-99m is a radioactive, artificial metal which can be produced in the clinic under sterile conditions. The half-life (HL) is approximately 6 hours. The total activity of technetium is stably bound to the zeolite. The proportion of the zeolite is between 0.30µm and 40 microns (colloids), amounting to approximately 25%. A total of 400mg of zeolite at 70MBq was administered orally to the subjects.

Test Procedure

6 minutes after administering the radioactive element, it can be detected in the stomach and the duodenum. The activity shifts 15 minutes after being taken from the stomach into the duodenum and, after 30 minutes, into the small intestine. 60 minutes after administering, the radiation is seen in the lower portion of the stomach, the duodenum and the entire small intestine. 120 to 180 minutes later there is no more detectable activity in the stomach. The marked MAC has now been transferred completely into the intestinal tract and, 240 minutes after administration, is also active in the large intestine. 24 hours after receiving MAC, shortly before excretion, the radiation is detected and is almost entirely in the section of the colon and rectum.
During the entire experiment no radiation signals were detected in the thyroid, lungs or kidneys. From this we conclude that no MAC particles that are bound to technetium-99 (TC99) were absorbed, otherwise even the slightest radioactivity in these organs would be detectable. Moreover, it should be noted that the TC99 would be completely absorbed when not coupled to MAC.This, too, would have lead to radioactivity in these organs.

Conclusion

The results of the experiment lead to the conclusion that activated clinoptilolite (MAC) is not absorbed in the human gastrointestinal tract. The main area of influence of MAC is based on the amount of time spent in the gastrointestinal tract, so the effects of the product can be concentrated here, where the binding of heavy metal and toxins and the promotion of the exchange mechanism (absorption, excretion, secretion) can occur. A final discussion is not possible at the present time with current understanding. Further, comprehensive studies need to be performed.