Histamine Intolerance (Histaminosis)

What is histamine intolerance ?

Histamine intolerance is rarely diagnosed by doctors and often goes unrecognised as the cause of many symptoms. Just like a food intolerance, many individuals are intolerant to histamine. The reason for this is that they have reduced levels of an enzyme in the digestive tract called diamine oxidase (DAO). DAO naturally breaks down and eliminates histamine. A deficiency in DAO means histamine is not being dealt with and is free to circulate in the body, where it can cause a wide range of symptoms.

Common symptoms include:

  • Rashes or hives
  • Headaches
  • Migraine
  • Diarrhoea
  • Circulatory problems
  • Itchy eyes
  • Runny nose/congestion
  • Cramping
There are many reasons a DAO deficiency might occur. It could due to genetics, gastrointestinal disorders, enzyme inhibition by medications, or a histamine rich diet. Ultimately, the result is an imbalance of histamine and DAO.

How does Toxaprevent help?

Toxaprevent PLUS Sachets and Capsules bind and eliminate excess histamine in the digestive tract. Once Toxaprevent binds to histamine, it is rendered harmless and is removed from the body through natural bowel movements. This reduces symptoms controlled by histamine and supports the body’s DAO enzyme.

The Sachets and Capsules contain the same active ingredient and both do the same job of removing histamine. However, you can pick which area of your digestive tract you want to target. The Sachets target the upper digestive tract (mouth, throat and stomach) and the Capsules by-pass the stomach, targeting only the lower digestive tract (small intestine and colon). Both can also be used together. In addition to Toxaprevent, a low-histamine diet should also be considered.


Take 2 - 3 Toxaprevent PURE Capsules before each main meal.

Mix the contents of 1 Toxaprevent PLUS Sachet in 300ml of water and drink in the morning to support the body’s DAO enzyme which naturally eliminates histamine. An extra sachet can also be taken at night if required.